Millions of people suffer GERD symptoms such as regular acid reflux, heartburn, coughing, wheezing, or hoarseness but don't know it.

GERD is a chronic digestive disease where the acids or contents of the stomach flow back into the food pipe (esophagus), injuring sensitive tissues. Our bodies produce stomach acid to help us digest our food. Stomach acid isn't a concern while it stays in the stomach. The lower esophageal sphincter (LES) helps keep stomach acid in the stomach. The LES relaxes to let food and drink in, then tightens to retain it. When the LES relaxes, stomach acid can escape into the esophagus. The stomach has a rigid lining that resists acid, but the food pipe does not. Its sensitive tissues are injured by acid, and other structures can be damaged if the acid makes its way to the mouth.

GERD, when left untreated, can result in severe life-threatening complications. The most common is Esophagitis, inflammation of the food pipe. It produces consistent burning pain that can make swallowing and eating difficult. If left untreated, the inflammation can cause ulcers of the tube's lining, bleeding, or both. Repeated cycles of Esophagitis and healing can lead to scarring and narrowing of the tube, known as Esophageal stricture. Ongoing damage to the esophagus caused by stomach acid can trigger cellular changes to the esophagus lining. It is a condition in which severe inflammation and acid conspire to produce premalignant changes in the cells that line the esophagus. With Barrett's esophagus, the squamous cells that line the lower esophagus are replaced by gland cells. Some 2% to 5% of people with Barrett's esophagus develop cancer.

Issued in Public Interest by Dr.Reddy's Laboratories LTD